Taking Galafold® (migalastat)

Alex, an actual Galafold patient.

Taking Galafold®

Below, hear from members of the Galafold community about how they fit Galafold into their lifestyles and see instructions on how to take Galafold.

Every other day is Galafold day.

Galafold is taken every other day at the same time of day and building Galafold into your routine can make it easier to remember.

“There was a component with incorporating a window of fasting before and after taking Galafold that I needed to become accustomed to. I found it very simple to fast once I started. For me, I stop eating two hours before I go to bed. I don’t even think about it after the medication because I’m asleep.”

- Rebecca, on her Galafold routine

You pick a pill time that's convenient for you.

Because Galafold needs to be taken at the same time of day on an empty stomach, pick a time that works best for you and your eating schedule. The time doesn’t matter, as long as you are consistent.

If a dose is missed you should take the missed dose of Galafold if it is within 12 hours of your normal schedule. If more than 12 hours have passed, do not make up the missed dose. You should resume taking Galafold at your next scheduled day and time according to your every-other-day dosing schedule.

“I put my Galafold package right next to my toothbrush. I see it at night as I am about to go to bed as I am brushing my teeth.”

- Alex, on his Galafold routine

You can have clear liquids around pill time.

Foods and certain liquids must be avoided at least 2 hours before and after pill time—but that doesn’t mean you have to avoid coffee, sodas, or juices. See below for the list of clear liquids you can have.

  • Water Plain, carbonated, or flavored
  • Juices No-pulp fruit juices like apple and grape
  • Sodas
  • Tea and Coffee No milk or cream

Packaging designed to help you take Galafold on schedule.

When life gets hectic, it can be hard to remember pill time – especially if Galafold is a new step in your routine. That’s why each Galafold pack is made to help you keep track.

“When I start a new package of Galafold, I like to write the day of the week above the capsule. I keep the package by my easy chair and it has become a habit to check it as the last thing I do before bed.”

- Joyce, on her Galafold tracking

Real Patients, Real Stories

Meet Joyce

Growing up, Joyce and her siblings experienced the same unexplained symptoms. But after 2 of her brothers were diagnosed with Fabry disease, Joyce knew it was time to see a genetic counselor. From there, she was enrolled in the Galafold trial and continues to take Galafold to treat her Fabry to this day.

Meet Alex

On his journey towards a Fabry diagnosis, Alex was misdiagnosed many times along the way. But as his symptoms continued to worsen, Alex and his wife were persistent in getting to the bottom of it. Eventually, Alex was diagnosed with Fabry disease and was the first person to take Galafold as a part of the clinical trials. In his words, Alex "learned how to take Galafold so that it worked for me."

Learn how to take Galafold with this step-by-step guide.

Lift the cover of your Galafold capsule carton.

Press and hold down the purple tab on the left side of the carton.

Hold the purple “pull” tab on the right side of the carton and pull out the blister card.

Unfold the blister card.
Tip: Press hard to allow the blister card to come out.

On your first day of taking a Galafold capsule from the new blister card, write the date on the blister card (Starting date).
Tip: It is important to take Galafold on an empty stomach. Do not eat at least 2 hours before and 2 hours after taking Galafold.

Remove the Galafold pill labeled Day 1, located on the bottom row and furthest to the left, by pressing the pill through the bottom of the blister card.
Tip: To avoid damaging the pill, press the bottom of the pill at an angle. Do not press the center of the capsule, as it may crush the pill. The pill should only be taken whole.

On the next day, remove the white cardboard circle labeled Day 2 on the top row and furthest to the left by pressing down on the circle. Removing this circle will help you remember which day you do not take Galafold. Take 1 Galafold pill only every other day.

The Galafold MyDay App was designed to help you keep track of your Galafold routine.

Check it out


Before taking Galafold® (migalastat), tell your healthcare provider about all of your medical conditions, including if you:

  • have kidney problems.
  • are pregnant or plan to become pregnant. It is not known if Galafold will harm your unborn baby.
  • have kidney problems.
  • are pregnant or plan to become pregnant. It is not known if Galafold will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. Galafold may pass into breast milk. Talk to your healthcare provider
    about the best way to feed your baby if you take Galafold.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Galafold?

The most common side effects of Galafold include headache, stuffy or runny nose and sore throat, urinary tract infection, nausea, and fever.

These are not all the possible side effects of Galafold. Call your healthcare provider for medical advice about side effects.

What is Galafold?

Galafold is a prescription medicine used to treat adults with Fabry disease who have a certain genetic change (variant) in the galactosidase alpha gene (GLA) that is responsive (amenable) to Galafold.

It is not known if Galafold is safe and effective in children.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Amicus Therapeutics at 1-877-4AMICUS.

Please click here for Full Prescribing Information, including Patient Information and Instructions for Use.