What is Galafold?
Galafold is a prescription medicine used to treat adults with Fabry disease who have a certain genetic change (variant) in an enzyme called alpha-galactosidase A (GLA) that is responsive (amenable) to Galafold.
It is not known if Galafold is safe and effective in children.
It is estimated that about 35% to 50% of patients living with Fabry disease have a genetic GLA variant that may be amenable to treatment with Galafold. Amenable means that a patient has a type of genetic GLA variant in which Galafoldis likely to respond. Only a clinical genetics professional can determine if you are eligible for treatment with Galafold.
Before taking Galafold, tell your healthcare provider about all of your medical conditions, including if you:
- have kidney problems.
- are pregnant or plan to become pregnant. It is not known if Galafold will harm your unborn baby.
- are breastfeeding or plan to breastfeed. Galafold may pass into breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Galafold.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Learn more by talking with your doctor about your genetic GLA variant.
Talk with your doctor if you have any questions or would like more information about Galafold.
The most common side effects of Galafold include:
- stuffy or runny nose and sore throat
- urinary tract infection
These are not all the possible side effects of Galafold. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
You may also report side effects to Amicus Therapeutics at 1-877-426-4287.
Talking with your doctor about your variant
Know which GLA variant you have
When you are diagnosed with Fabry disease, your doctor usually performs a test that informs him or her about which GLA variant you have. This is important because it can affect how your disease progresses and how you manage it. Your doctor may also suggest that you get genetic counseling and that other family members get tested for the disease.